import numpy as np
import codecs, json 

a = np.arange(10).reshape(2,5) # a 2 by 5 array
b = a.tolist() # nested lists with same data, indices
file_path = "/path.json" ## your path variable
json.dump(b, codecs.open(file_path, 'w', encoding='utf-8'), separators=(',', ':'), sort_keys=True, indent=4) ### this saves the array in .json format

关键是tolist和codecs编码，并转成适应json的格式。

解码并还原：

obj_text = codecs.open(file_path, 'r', encoding='utf-8').read()
b_new = json.loads(obj_text)
a_new = np.array(b_new)

转自：https://stackoverflow.com/questions/26646362/numpy-array-is-not-json-serializable